ANALYTICAL TEST PROCEDURE OF SODIUM BENZOATE

 

MATERIAL NAME:  SODIUM  BENZOATE
Molecular Formula: C7H5NaO2	Formula Weight: 144.10	Equivalent Weight: 144.1

 

SL NO.	Test Parameters	Specification
1.	Physical State	White Crystalline or granular Powder
2.	Identification	1. When a solution of benzoate (1g in 20 ml of water) is acidified with dilute HCl, crystalline ppt is formed. 2. When FeCl3 solution is added to a neutral solution of benzoate (1g in 20 ml of water), reddish brown ppt is formed.
3.	Clarity	5 % W/W Solution Should Be Clear Compared With Existing Good One
4.	Loss on drying	NMT 2.0% w/w at 105°C for 15 minutes, use 1 g
5.	Assay (%)	99.0 % to 100.5 % as C6H8O7 calculated on anhydrous basis.

 

METHOD OF ASSAY ANALYSIS

1. Place About 0.6 g Of Accurately Weighed sample to a 250 ml conical flask. 2. Add 100 ml of glacial acetic acid & dissolve properly. 3. Add 2 drops of crystal violate TS. 3. Titrate With 0.1 N Perchloric acid VS untill  green color appeared. 4. Perform a blank titration .

 

CALCULATION OF ASSAY PERCENTAGE

Each ml Of 0.1 N  perchloric acid  Is Equivalent To 14.41 mg Of  C7H5NaO2

Precautions:

                            1. Standardize   Per chloric acid  Solution Before Titration.

                          2. Weighing Should Be Accurate

REFERENCE: USP-29